Metastatic Pancreatic Neuroendocrine Tumor with Ectopic Adrenocorticotropic Hormone Production
نویسندگان
چکیده
منابع مشابه
Metastatic pancreatic neuroendocrine tumor with ectopic adrenocorticotropic hormone production.
We describe a 71-year-old man who presented with abdominal pain, lower-extremity edema, recent unintentional weight loss, hypertension, hyperglycemia, hypokalemia, and metabolic alkalosis. Serum cortisol levels remained elevated after overnight high-dose dexamethasone suppression. Magnetic resonance imaging revealed a small mass in the head of the pancreas with scattered liver metastases. Both ...
متن کاملMetastatic Pancreatic Neuroendocrine Tumor that Progressed to Ectopic Adrenocorticotropic Hormone (ACTH) Syndrome with Growth Hormone-releasing Hormone (GHRH) Production
The patient was a 61-year-old woman who had a well-differentiated pancreatic neuroendocrine tumor (PNET) with lymph node metastasis. After 15 months of octreotide treatment, glucose control deteriorated and pigmentation of the tongue and moon face developed, leading to the diagnosis of ectopic adrenocorticotropic hormone (ACTH) syndrome. An abnormal secretion of growth hormone (GH) was identifi...
متن کاملThymic neuroendocrine carcinoma producing ectopic adrenocorticotropic hormone and Cushing's syndrome.
Neuroendocrine carcinoma of the thymus, previously termed thymic carcinoid, is a rare clinical entity. Rarer still are such cases presenting with endocrinopathies. We report a case of thymic neuroendocrine carcinoma presenting with ectopic adrenocorticotroic hormone production and resultant Cushing's syndrome.
متن کاملPulmonary adenocarcinoma presenting with symptoms of ectopic adrenocorticotropic hormone production
General physical examination revealed clubbing and hyperpigmentation of both hands and feet. There was Grade 5 power in all the limbs. Laboratory investigations revealed hypokalemia (1.3 meq/L), metabolic alkalosis (pH = 7.52, serum bicarbonate = 39.8 mmol/L), hyperglycemia (fasting blood glucose = 308 mg%), elevated serum cortisol levels (75 mg/dl, normal reference range 7–23 mg/dl), and high ...
متن کاملCushing syndrome secondary to ectopic adrenocorticotropic hormone secretion from a Meckel diverticulum neuroendocrine tumor: case report
BACKGROUND Ectopic production of adrenocorticotropic hormone (ACTH) by neuroendocrine tumours (NET) is a rare condition, occult presentations often hampering the diagnosis. Although NET are relatively frequent in the ileon and Meckel diverticulum, we describe the first Cushing's syndrome due to ectopic adrenocorticotropic syndrome (CS-EAS) arising from a Meckel diverticulum. CASE PRESENTATION...
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ژورنال
عنوان ژورنال: Baylor University Medical Center Proceedings
سال: 2015
ISSN: 0899-8280,1525-3252
DOI: 10.1080/08998280.2015.11929184